Anesthesia EEG Simulator
Phase-Amplitude Coupling
Created by Dra. Carolina Frederico
Educational use only
Slow delta rhythm
Standard phase convention: 90 deg = delta peakAlpha rhythm modulated by delta phase
Black: delta + alpha, red: alpha rhythm, green: amplitude envelopePhase reference
Current delta phasePhase-amplitude histogram
Mean alpha amplitude by delta phase
Clinical idea: PAC is not simply more alpha or more delta. It describes whether alpha amplitude is organized by the phase of a slower rhythm. The number is useful only together with the spectrogram, signal quality, drug state, and brain vulnerability.
